Exosomes and Pixel RF Microneedling.

What is Pixel RF Microneedling?

Pixel RF is a fractional microneedling device that combines:

• Precision micro-needles

• Targeted radiofrequency heat

• Controlled micro-channels into the skin

Pixel RF can support improvements in:

• Skin texture

• Skin tone

• Fine, mild crepey areas

• Overall rejuvenation pathways

The combination of microneedles and gentle RF heat places the skin into a highly receptive state, making it an ideal time to apply supportive topicals such as exosomes.

Why Are Exosomes and Microneedling Used Together?

This combination is popular because the skin is particularly open and responsive after microneedling.

Together, they may:

• Allow exosomes to move through the freshly created micro-channels
• Support early healing pathways
• Help the skin feel calmer
• Replenish moisture lost during treatment
• Reduce visible redness for some people
• Provide a nurturing layer during recovery

No promises, simply potential supportive benefits

How Exosomes May Support Skin Rejuvenation After Pixel RF Microneedling

Potential supportive benefits:

• Help the skin feel more comfortable
• Assist with hydration
• Contribute to smoother-feeling skin during the recovery period
• Help reduce prolonged redness for some
• Works as a complementary post-treatment layer

Are Exosomes better than other post-treatment options?

Not necessarily — exosomes are just one option.
Other supportive options include: 

• Hyaluronic acid serums
• LED light therapy
• PRP (if appropriate)
• Cooling masks
• Restorative barrier-support skincare

Some clients enjoy the comfort exosomes offer. Others prefer traditional options. Suitability depends on your skin and treatment goals.

The Science Behind Algizome

At the heart of Algizome is Chlamydomonas reinhardtii Vesicles (exosome-like vesicles) created using a patented biomimetic exosome technology.
These laboratory-created vesicles are derived from green microalgae and are designed to mirror the structure and signalling behaviour of human fibroblast exosomes.

Unlike conventional extracts or isolated molecules, this technology encapsulates the complete bioactive profile of the microalgae — essentially harnessing one of nature’s most efficient communication systems.

These vesicles act as intelligent messengers, helping support:

• Collagen

• Elastin

• Hyaluronic acid

• Fibronectin

• Fibrillin

All key components of a healthy extracellular matrix.

Each 30 mL bottle contains over 10.6 billion vesicles, offering a high dose of supportive signalling designed to promote firmness, hydration and overall skin resilience.

Synergie Exomimic technology:

• “Exosome science, fluent in skin”

• “Smart signals. Stronger skin.”

• “Your skin’s new conversation starter.”

While Algizome is not an exosome treatment in the medical sense, it aligns beautifully with what we aim to support after Pixel RF: calmer, stronger, more hydrated skin.

Who May Be Suitable for Exosomes and Microneedling?

May suit those wanting:

• Gentle skin rejuvenation
• Support during healing
• Hydration and post-treatment comfort
• Non-surgical treatment options

Suitability always depends on:

• Skin type
• Medical history
• Current skincare
• Treatment expectations

We assess this carefully during your consultation.

Frequently Asked Questions

What exosomes or supportive vesicles do you use?
We use Synergie Skin Algizome as our preferred topical support. It contains biomimetic vesicles designed to help calm and hydrate the skin.

Are exosomes the same as stem cells?
No. Exosomes are tiny cellular messengers. They do not contain stem cells, and they don’t behave like stem cells. They’re topical, not implanted.

Why are exosomes used after microneedling?
The micro-channels created by microneedling may allow exosomes to settle more effectively onto the skin and support the early healing phase.

Can exosomes replace PRP?
Not necessarily. PRP comes from your own blood, while exosomes are a topical product. They can both support the skin in different ways. Suitability depends on skin condition and preferences.

Does everyone benefit from adding exosomes?
No, some people find that their skin settles more comfortably, while others prefer traditional post-treatment skincare. We assess whether it’s worthwhile for your skin.

How does Pixel microneedling differ from standard microneedling?
Pixel combines RF heat with microneedling, creating more uniform micro-channels and a deeper supportive response.

How soon after Pixel microneedling are exosomes applied?
Immediately, the timing is intentional for optimal absorption.

Can exosomes be used in multiple sessions?
Yes, they can be incorporated into a series of treatments if appropriate, but this depends on skin response and your treatment plan.

Do exosomes change the downtime?
Some people report their skin feels calmer earlier, but downtime varies. We always give personalised aftercare based on how your skin presents.

Is this treatment safe?
Safety is assessed based on your medical history and skin condition.

Is the combination right for everyone?
Not always. That’s why the consultation is important, and we tailor your treatment plan to your skin and your expectations.

Is there an at-home Exosome skincare?

Algizome and Synergie’s Super Serum create an excellent at-home routine to complement in-clinic treatments.

Get in touch

If you’re curious about exosomes and microneedling, or simply looking for gentle guidance on where to begin with skin rejuvenation, you’re always welcome at Aesthetica Image Centre.

We’ve supported thousands of women and men over the years — with honesty, kindness and time to talk through your options properly.